Poppy Leitch starts at openside and is one of seven changes to the side that lost 52-17 to Canada last Friday.
Captain Sarah Hunter partners Leitch in the back row and earns her 80th cap for her country, while Amber Reed and Katie Mason retain their positions at fly-half and wing respectively.
Front row forward Sarah Bern will win her first cap off the bench and Izzy Noel-Smith is also named in lead coach Scott Bemand’s matchday 23.
The match kicks off at 10pm BST at the Regional Athletic Complex, Salt Lake City, and is broadcast live on TheRugbyChannel.tv.
England and France last played in the final game of the 2016 Six Nations, where France, playing at home, narrowly saw off England 17-12 to clinch the title.
